Results of deep brain stimulation for dystonia: A critical reappraisal
Identifieur interne : 000467 ( France/Analysis ); précédent : 000466; suivant : 000468Results of deep brain stimulation for dystonia: A critical reappraisal
Auteurs : Laurent Vercueil [France] ; Paul Krack [France] ; Pierre Pollak [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2002-03.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Bibliographic survey, Brain (vertebrata), DBS, Dystonia, Dystonia (surgery), Dystonia (therapy), Electric Stimulation Therapy, Electrodes, Implanted, Evolution, Globus Pallidus (surgery), Human, Humans, Instrumental stimulation, Stereotaxic Techniques, Treatment, Treatment Outcome, dystonia, globus pallidus, stereotaxia.
- MESH :
- surgery : Dystonia, Globus Pallidus.
- therapy : Dystonia.
- Electric Stimulation Therapy, Electrodes, Implanted, Humans, Stereotaxic Techniques, Treatment Outcome.
Abstract
Deep brain stimulation for severe dystonia is still in the very first stage of development. Only single case reports or small case series have been reported to date. Best results have been obtained with pallidal stimulation in patients with primary generalised dystonia, especially in DYT1 mutation carriers. In secondary dystonia, conflicting results were reported. However, there is today enough promising evidence for a striking efficacy of pallidal stimulation in dystonia, supporting the need for further investigations in the field, with collaborative projects (regarding to the limited number of eligible patients); double‐blind studies, including a consensus about surgical method; and a precise anatomic analysis of the position of the electrode. A careful assessment of the efficacy by using improved clinical scale is also warranted. © 2002 Movement Disorder Society
Url:
DOI: 10.1002/mds.10148
Affiliations:
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